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分子細胞生物学
構造生物学
32246052 Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses. Communications biology 2020 Apr;3(1):163. Oikawa D,Sato Y,Ohtake F,Komakura K,Hanada K,Sugawara K,Terawaki S,Mizukami Y,Phuong HT,Iio K,Obika S,Fukushi M,Irie T,Tsuruta D,Sakamoto S,Tanaka K,Saeki Y,Fukai S,Tokunaga F 0 2020-11-24
分子細胞生物学 32559497 Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer. Cancer cell 2020 Aug;38(2):198-211.e8. Escobar-Hoyos LF,Penson A,Kannan R,Cho H,Pan CH,Singh RK,Apken LH,Hobbs GA,Luo R,Lecomte N,Babu S,Pan FC,Alonso-Curbelo D,Morris JP,Askan G,Grbovic-Huezo O,Ogrodowski P,Bermeo J,Saglimbeni J,Cruz CD,Ho YJ,Lawrence SA,Melchor JP,Goda GA,Bai K,Pastore A,Hogg SJ,Raghavan S,Bailey P,Chang DK,Biankin A,Shroyer KR,Wolpin BM,Aguirre AJ,Ventura A,Taylor B,Der CJ,Dominguez D,Kümmel D,Oeckinghaus A,Lowe SW,Bradley RK,Abdel-Wahab O,Leach SD 0 2020-11-15
分子細胞生物学 32641828 Envelope protein ubiquitination drives entry and pathogenesis of Zika virus. Nature 2020 09;585(7825):414-419. Giraldo MI,Xia H,Aguilera-Aguirre L,Hage A,van Tol S,Shan C,Xie X,Sturdevant GL,Robertson SJ,McNally KL,Meade-White K,Azar SR,Rossi SL,Maury W,Woodson M,Ramage H,Johnson JR,Krogan NJ,Morais MC,Best SM,Shi PY,Rajsbaum R 0 2020-11-12
数理解析 33096023 Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells. Cancer cell 2020 Oct;():. Kuenzi BM,Park J,Fong SH,Sanchez KS,Lee J,Kreisberg JF,Ma J,Ideker T 0 2020-11-10
分子細胞生物学 31995728 AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System. Molecular cell 2020 03;77(5):951-969.e9. Jia J,Bissa B,Brecht L,Allers L,Choi SW,Gu Y,Zbinden M,Burge MR,Timmins G,Hallows K,Behrends C,Deretic V 0 2020-10-16
分子細胞生物学 32160526 A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation. Cell 2020 03;180(6):1160-1177.e20. Liang JR,Lingeman E,Luong T,Ahmed S,Muhar M,Nguyen T,Olzmann JA,Corn JE 0 2020-10-16
分子細胞生物学 32610081 Ribosome Collisions Trigger General Stress Responses to Regulate Cell Fate. Cell 2020 Jul;182(2):404-416.e14. Wu CC,Peterson A,Zinshteyn B,Regot S,Green R 0 2020-10-12
分子細胞生物学 32555459 Senolytic CAR T cells reverse senescence-associated pathologies. Nature 2020 07;583(7814):127-132. Amor C,Feucht J,Leibold J,Ho YJ,Zhu C,Alonso-Curbelo D,Mansilla-Soto J,Boyer JA,Li X,Giavridis T,Kulick A,Houlihan S,Peerschke E,Friedman SL,Ponomarev V,Piersigilli A,Sadelain M,Lowe SW 0 2020-09-26
分子細胞生物学 31511697 DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome. Nature 2019 09;573(7775):590-594. Samir P,Kesavardhana S,Patmore DM,Gingras S,Malireddi RKS,Karki R,Guy CS,Briard B,Place DE,Bhattacharya A,Sharma BR,Nourse A,King SV,Pitre A,Burton AR,Pelletier S,Gilbertson RJ,Kanneganti TD 0 2020-08-17
その他 32391793 AirID, a novel proximity biotinylation enzyme, for analysis of protein-protein interactions. eLife 2020 May;9():. Kido K,Yamanaka S,Nakano S,Motani K,Shinohara S,Nozawa A,Kosako H,Ito S,Sawasaki T 0 2020-08-02
その他 32512835 A Human DUB Protein Array for Clarification of Linkage Specificity of Polyubiquitin Chain and Application to Evaluation of Its Inhibitors. Biomedicines 2020 Jun;8(6):. Takahashi H,Yamanaka S,Kuwada S,Higaki K,Kido K,Sato Y,Fukai S,Tokunaga F,Sawasaki T 0 2020-07-27
分子細胞生物学 31973890 p53 Activates the Long Noncoding RNA Pvt1b to Inhibit Myc and Suppress Tumorigenesis. Molecular cell 2020 02;77(4):761-774.e8. Olivero CE,Martínez-Terroba E,Zimmer J,Liao C,Tesfaye E,Hooshdaran N,Schofield JA,Bendor J,Fang D,Simon MD,Zamudio JR,Dimitrova N 0 2020-04-27
分子細胞生物学 31792379 Phase separation of YAP reorganizes genome topology for long-term YAP target gene expression. Nature cell biology 2019 12;21(12):1578-1589. Cai D,Feliciano D,Dong P,Flores E,Gruebele M,Porat-Shliom N,Sukenik S,Liu Z,Lippincott-Schwartz J 0 2020-04-18
分子細胞生物学 31221965 Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer. Nature communications 2019 06;10(1):2701. Jin N,Bi A,Lan X,Xu J,Wang X,Liu Y,Wang T,Tang S,Zeng H,Chen Z,Tan M,Ai J,Xie H,Zhang T,Liu D,Huang R,Song Y,Leung EL,Yao X,Ding J,Geng M,Lin SH,Huang M 0 2020-04-03
分子細胞生物学 30955890 Insulin Receptor Associates with Promoters Genome-wide and Regulates Gene Expression. Cell 2019 04;177(3):722-736.e22. Hancock ML,Meyer RC,Mistry M,Khetani RS,Wagschal A,Shin T,Ho Sui SJ,Näär AM,Flanagan JG 0 2020-03-31
分子細胞生物学 31289211 The L-type amino acid transporter LAT1 inhibits osteoclastogenesis and maintains bone homeostasis through the mTORC1 pathway. Science signaling 2019 Jul;12(589):. Ozaki K,Yamada T,Horie T,Ishizaki A,Hiraiwa M,Iezaki T,Park G,Fukasawa K,Kamada H,Tokumura K,Motono M,Kaneda K,Ogawa K,Ochi H,Sato S,Kobayashi Y,Shi YB,Taylor PM,Hinoi E 0 2020-03-09
分子細胞生物学 30858571 Aedes aegypti AgBR1 antibodies modulate early Zika virus infection of mice. Nature microbiology 2019 06;4(6):948-955. Uraki R,Hastings AK,Marin-Lopez A,Sumida T,Takahashi T,Grover JR,Iwasaki A,Hafler DA,Montgomery RR,Fikrig E 0 2020-03-02
分子細胞生物学 32029622 An AMPK-caspase-6 axis controls liver damage in nonalcoholic steatohepatitis. Science (New York, N.Y.) 2020 02;367(6478):652-660. Zhao P,Sun X,Chaggan C,Liao Z,In Wong K,He F,Singh S,Loomba R,Karin M,Witztum JL,Saltiel AR 0 2020-02-21
数理解析 31142858 Longitudinal multi-omics of host-microbe dynamics in prediabetes. Nature 2019 05;569(7758):663-671. Zhou W,Sailani MR,Contrepois K,Zhou Y,Ahadi S,Leopold SR,Zhang MJ,Rao V,Avina M,Mishra T,Johnson J,Lee-McMullen B,Chen S,Metwally AA,Tran TDB,Nguyen H,Zhou X,Albright B,Hong BY,Petersen L,Bautista E,Hanson B,Chen L,Spakowicz D,Bahmani A,Salins D,Leopold B,Ashland M,Dagan-Rosenfeld O,Rego S,Limcaoco P,Colbert E,Allister C,Perelman D,Craig C,Wei E,Chaib H,Hornburg D,Dunn J,Liang L,Rose SMS,Kukurba K,Piening B,Rost H,Tse D,McLaughlin T,Sodergren E,Weinstock GM,Snyder M 0 2020-02-19
分子細胞生物学 32049023 SENP3 Suppresses Osteoclastogenesis by De-conjugating SUMO2/3 from IRF8 in Bone Marrow-Derived Monocytes. Cell reports 2020 Feb;30(6):1951-1963.e4. Zhang Y,Yang K,Yang J,Lao Y,Deng L,Deng G,Yi J,Sun X,Wang Q 0 2020-02-16